Primary biliary cirrhosis pbc is an autoimmune cholestatic liver disease in which the biliary epithelial cells lining the small intrahepatic bile ducts are the target for immune mediated damage although ranking far below hepatitis viruses and alcohol related liver diseases pbc is an important cause of chronic liver disease worldwide and in the western world it represents one of the most . Clinics in liver disease 76 citescore 4623 impact factor articles issues about publish guide for authors menu articles issues latest issue all issues article collections sign in to set up alerts rss about publish guide for authors search in this journal primary biliary cirrhosis ej heathcote volume 7 issue 4 pages 735 992 november 2003 download full issue . Primary biliary cholangitis previously called primary biliary cirrhosis is a chronic disease in which the bile ducts in your liver are slowly destroyed bile is a fluid made in your liver it aids with digestion and helps your body get rid of cholesterol toxins and worn out red blood cells. Primary biliary cirrhosis of the liver is an autoimmune liver disease that begins as a chronic destructive non venous cholangitis which lasts for a long time without significant symptoms leading to the development of prolonged cholestasis and only at later stages to the formation of liver cirrhosis. Primary biliary cirrhosis an issue of clinics in liver disease 1e the clinics internal medicine nov 13 2020 posted by mary higgins clark library text id 29528609 online pdf ebook epub library small intrahepatic bile ducts are the target for immune mediated damage primary biliary cirrhosis pbc is a disease of the liver in which the bile ducts slowly become